The $158 billion smart home market is booming — but 90% of one category is untouched. RYSE is the only company automating it.

Company behind CrowdEcho

Osteoboost is the first and only FDA-cleared prescription wearable device specifically designed to treat osteopenia in postmenopausal women, filling a critical treatment gap for over 50 million Americans with low bone density. Named a TIME Best Invention of 2025, this breakthrough medical device delivers precise, calibrated vibration therapy directly to the spine and hips—the areas most vulnerable to osteoporotic fractures. In a gold-standard 12-month clinical trial at the University of Nebraska Medical Center, Osteoboost demonstrated remarkable results: 85% reduction in spine bone density loss, 83% reduction in bone strength loss, and 55% reduction in hip bone density loss—all with zero serious adverse events. The comfortable belt worn for just 30 minutes daily during normal activities like walking or cooking, uses NASA-inspired technology originally developed for astronauts. Cleared through FDA's De Novo pathway with Breakthrough Device designation, Osteoboost offers a drug-free alternative that patients describe as feeling like a gentle massage. Available by prescription for $995 (special launch price), includes free 1-year access to Wellen exercise program, 30-day money-back guarantee, and 1-year warranty. Currently shipping 8-12 weeks after order with free delivery from partner pharmacy.

Myosana Therapeutics is a Seattle-based biotechnology company revolutionizing gene therapy for neuromuscular and cardiac diseases through its breakthrough non-viral delivery platform. Founded in 2018 by University of Washington experts Dr. Stan Froehner and Dr. Nick Whitehead, we're overcoming the critical limitations of traditional viral gene therapy. Our proprietary platform uses GLUT4 protein-targeting antibodies to deliver full-length genes directly to skeletal and cardiac muscle cells—without size restrictions that limit AAV therapies. This enables treatment of diseases requiring large genes like Duchenne muscular dystrophy (DMD), where we can deliver the complete dystrophin gene rather than truncated versions.

Company behind Scum & Villainy Cantina: Rendezvous

Company behind Movie: Playbook of Johnny

EMulate has solved one of medicine's most elusive challenges: delivering therapeutic benefits without physical drugs.

Company behind HLTHI

MASK NextGen: AI-Driven Cyber Safety for Kids, One Click at a Time

Company behind Remi Therapeutics

Our patented technology transforms standard household outlets into fast 240V charging stations, instantly unlocking the massive apartment-dwelling EV market competitors can't reach. No construction, no permits, no capital expenditure—just plug-and-profit scalability.

We are a community development corporation a non-profit with the intention to empower and share wellness practices and help others through the process of awakening to the real perceptions of the universe and empowerment encouragement for self sufficiency. Our activities are for the support and empowerment of our clients to be the best version of themselves. Most of our clients are the unhoused/homeless community as we help them with a hand up and not just a hand out. Please join us as we make a difference in the lives of those who need us.

Aevumed is a cutting-edge medical device company specializing in revolutionary orthopedic implants and instruments for soft tissue repair, particularly rotator cuff surgeries. Our FDA-cleared PHANTOM® series suture anchors feature proprietary BoneShield™ Technology and adjustable tension control, addressing the critical problem of re-tears that affect 20-50% of rotator cuff repair patients. Founded by industry veterans with a clinical-first approach, we combine 3D printing, AI-driven innovation, and direct surgeon collaboration to deliver superior surgical outcomes. Based in Malvern, PA, with growing national presence in hospitals across the US. Perfect for orthopedic surgeons seeking advanced, minimally invasive solutions for sports medicine and extremity procedures.

The World's First Holistic Health Hub—Find What You Need, When You Need It

Crowdigy is a fundraising advisory firm and a social business marketplace for funders and founders to connect, share and grow.

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For people who value Content and Community, Fanbase is a free to download, free to use, next-generation social network that allows any user to earn money from day one.

AvaWatz's AI platform enables robots to collaborate effectively in high-risk environments - from hazardous material handling to infrastructure maintenance and military operations - while keeping humans out of harm's way. Our system coordinates diverse robotic, visual, and sensor technologies to execute critical tasks including maintenance, surveillance, and safety inspections.

CypherShield builds AI-driven solutions for diverse industries, founded by a cybersecurity architect to ensure robust security at every level. From advanced email protection to consensus frameworks, we drive secure, scalable innovation.

StockText, with a valuation of $7.4 million, is raising funds on NetCapital. The company has developed a platform that works as a personal stock alert assistant for public and private securities. StockText will help investors with real-time alerts on stock price changes and other important market information sent directly to their email and phones. The business will start on a freemium model as the first tier and will subsequently move to a premium subscription model to include analyst reports. Mario Hernandez founded StockText in November 2023. The current crowdfunding campaign has a minimum target of $10,000 and a maximum target of $124,000. The campaign proceeds will be used for technology, marketing, and general and administrative expenses.

Sherpa Aircraft, with a valuation of $95 million, is raising funds on Dealmaker Securities. The company makes the next-generation commercial extreme STOL aircraft with short-takeoff and landing aviation. Sherpa Aircraft are manufactured for consistent reliability and custom adaptability in the most challenging operations and can be manoeuvred with or without airports. The company caters to commercial and private applications and impacts a variety of sectors, including military, state, and local government. Wesley Gordon and Scot Warren founded Sherpa Aircraft in February 2023. The current crowdfunding campaign has a minimum target of $47,500 and a maximum target of $4.9 million. The campaign proceeds will be used for capital acquisition, development, general operating costs, and working capital.

Lia27, with a valuation of $45 million, is raising funds on DealMaker Securities. It is one of the first human-like AI assistants that is built to deliver human-like interactions at scale. Lia27 is the AI revolution investors have been waiting for, as it is designed to manage tasks seamlessly and connect emotionally to provide assistance along with empathetic support. The business is a member of the Google AI Startup Program and has proven organic growth, with each user referring 5.6 new users. Jean-Francois Comeau and Alexandre Dufresne founded Lia27 in October 2024. The current crowdfunding campaign has a minimum target of $10,000.27 and a maximum target of $5 million. The campaign proceeds will be used for technology and product development, sales and marketing, infrastructure, and general working capital.

Cold Zero is raising funds on Main Street Bond. The veterans-owned company distills and bottles its premium spirits with Cedar Ridge Distillery in Swisher, Iowa. Cold Zero aims to build a reputation for its premier vodka and bring its whiskey into the spotlight. The company also donates a portion of its profits to organizations that enrich the lives of active-duty service members, their families, and the veteran community. Chad Williams and Casey Maxted founded Cold Zero in July 2021. The current crowdfunding campaign has a minimum target of $40,000 and a maximum target of $1.2 million. The campaign proceeds will be used to fund national distribution and field marketing initiatives to ensure sustainable growth in sales.

2MDOpinion, with a valuation of $14 million, is raising funds on NetCapital. The company provides patients with trusted health advice and global medical second opinions. 2MDOpinion uses IBM AI to generate EMR reports and translates audio in over 90 languages across 48 specialties in North America and the Middle East. The platform works for patients looking for the reassurance of a well-informed medical decision in their own language or the availability of an alternative treatment plan. Amr Bannis founded 2MDOpinion in November 2023. The current crowdfunding campaign has a minimum target of $10,000 and a maximum target of $1 million. The campaign proceeds will be used for development and support, marketing, asset operating expenses, and employee compensation.